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KMID : 0387720220330010046
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Korean Journal of Blood Transfusion
2022 Volume.33 No. 1 p.46 ~ p.49
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Comparison between Screening Cells Including Dia and Mia Antigen for Unexpected Antibody Screening
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Shin Kyung-Hwa
Kim Hyung-Hoi
Lee Hyun-Ji
Kim Hye-Rim
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Abstract
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The Dia and Mia antigens have been detected in Koreans with a frequency of 6.4∼14.5% and 0.9%, respectively.
This study evaluated the effectiveness of different screening cells using the cells with Dia and Mia antigens for unexpected antibody screening. An unexpected antibody-screening test was performed separately using different screening cells, including the Dia antigen (Panel D) and Mia antigen (Panel M). A total of 2,077 specimens from 1,847 patients were collected, among which 49 (2.32%) and 43 (2.08%) were positive using Panel D and Panel M, respectively. Twenty-seven patients were positive with both panels, 2012 were negative with both panels, and thirty-eight patients showed a discordant result. The suspected anti-Dia and anti-Mia were detected in 4 (0.19%) and 5 (0.24%) patients, respectively. Therefore, the frequency of anti-Dia and anti-Mia antibodies in this study may be helpful for selecting unexpected antibody screening reagents.
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KEYWORD
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Diego, Miltenberg, Antibody screening
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